Sunday, July 21, 2013

10-12 Business Club Twyford Mixed, The Bird In Hand, Twyford

The 10-12 Business Club is for women and Men in business looking to network with like minded women in a structured environment. As well as open networking we have educational slots and presentations on business issues that may help you in the development of your own business.

Our meetings are held once per month and chaired by Karen Livingstone of Little Acorn Marketing.

We have a full agenda and our open networking starts with 20 minutes of informal but slightly structured networking. At 10.20 we will ask you to take a seat for the main part of the meeting to begin. Below is a brief description of the format for the mornings meeting:

Mornings Agenda

? Business Card Exchange (Bring lots of cards with you)

? Individual personal introduction no more than 40 seconds.

? Informative talk or presentation by a member or guest speaker (10 minutes total)

? Educational Module (10minutes)

? 4xs 10 minute 1-2-1s

? Round up of meeting asking each attendee for any Success Stories, Action Points or Testimonial

? Future Events /Membership

? Close 11.50 to allow time for follow up

We look forward to meeting you at the next 10-12 Business Club Meeting.

Event Organised By

10 to12 Business Club

www.10-12BusinessClub.co.uk

The 10-12 Business Club is for *women in business looking to network with like minded women in a structured environment. As well as open networking we have educational slots and presentations on business issues that may help you in the development of your own business.

Our meetings are held once per month and chaired by:

Reading Group: Issy Wiggins-Turner from Where's Your Web Site

Marlow Group: Karen Livingstone from Little Acorn Marketing

Sunningdale Group: Lucie Robson from Off the Red Tees

Twyford Mixed Group: Karen Livingstone from Little Acorn Marketing

We have a full agenda and our open networking starts with 20 minutes of informal but slightly structured networking. At 10.20 we will ask you to take a seat for the main part of the meeting to begin. Below is a brief description of the format for the mornings meeting:

Mornings Agenda

? Business Card Exchange (Bring lots of cards with you)

? Individual personal introduction no more than 40 seconds.

? Informative talk or presentation by a member or guest speaker (10 minutes total)

? Educational Module (10minutes)

? 4xs 10 minute 1-2-1s

? Round up of meeting asking each attendee for any Success Stories, Action Points or Testimonial

? Future Events /Membership

? Close 11.50 to allow time for follow up

We look forward to meeting you at the next 10-12 Business Club Meeting.

*The 10-12 Business Club currently have one mixed group held in Twyford Berkshire the 4th Wednesday of each month.

Attending this event or want to share it on Facebook? Comment below!

Source: http://www.findnetworkingevents.com/events/index.cfm?action=eventdetail&eventid=57889&utm_source=sitefeeds&utm_medium=rss&utm_campaign=regionfeed

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Adam Scott collapses again in British Open

GULLANE, Scotland (AP) ? Adam Scott's collapse in the final round at the British Open wasn't nearly as spectacular as it was a year ago.

The end result was still the same.

For the second year in a row Scott held the lead on the back nine; for the second year in a row he left without his name on the claret jug.

Even the green jacket he won in between at the Masters couldn't ease the sting of this one.

"I think the disappointing thing is this one I felt I wasted a little bit," Scott said Sunday. "I would have liked to be in at the end and no one was, actually. It's a shame."

No one was because Phil Mickelson closed so strongly he likely would have won the Open no matter what Scott or any of his fellow competitors did. But three straight bogeys on the back nine sealed the fate of the Masters champion, eliminating him from contention before he even had a shot at making a late run.

"I let a great chance slip, I felt, during the middle of the round and that's disappointing," Scott said. "Had I played a little more solid in the middle of that back nine I could have had a chance coming in."

Playing in the next-to-last group with Tiger Woods, Scott made a run at the lead when he sank a long putt on the eighth hole for birdie, then followed it with a two-putt birdie on the par-5 ninth. When he added yet another birdie on the short par-4 11th he was suddenly in the lead with seven holes to go.

Nothing new there. Last year at the Open at Lytham, Scott had a four-shot lead with four holes to play and all that seemed left to do was prepare his victory speech.

It quickly unraveled, though, with Scott finishing with a string of bogeys in one of the great collapses in golfing history. The image of his knees buckling when he missed a 7-foot putt to force a playoff with Ernie Els lingers still.

Compared to that, Sunday's back nine missteps paled by comparison. Once again, though, Scott began making bogeys and soon someone else was holding the Open trophy.

It began with a bad shot into the grassy dunes right of the 13th green that Scott almost got away with when he hit a great pitch to seven feet. But the putt lipped out, beginning a string of three straight bogeys that took him out of contention.

"I didn't get to the number that Phil finished on, but I was right there," Scott said. "Had I played a little more solid in the middle of that back nine, I could have had a chance coming in."

Scott's disappointment in a wasted opportunity was tempered by the fact Mickelson shot a 5-under 66 to finish the tournament at 3-under-par. But Scott was 2-under himself after the 11th hole, and it wasn't outside the realm of possibility that he might have made a few more birdies coming in.

He wasn't certain where he stood as he made his way into the back nine, though he had an idea Mickelson was making a move.

"The boards weren't working really very good," Scott said. "I had a look a couple of times, but they didn't really seem to make so much sense. I wasn't sure if they had it right. Phil kept moving up."

By the time Scott rolled in a final 20-footer on the last hole for birdie, Mickelson was already doing interviews and signing autographs off the final green. Scott finished four shots back, tied for third with third-round leader Lee Westwood and Ian Poulter.

Scott and Woods had a brief chat as they left the green, both feeling they had let one get away.

"It was just generic stuff," he said. "I think we both just kind of were disappointed with our performance today, to be honest."

That wasn't the case in April when the Australian with the long putter strung together a pair of 69s on the weekend to get into a playoff with Angel Cabrera to win the Masters. It was a breakthrough win for the 32-year-old, and especially satisfying since it came in the wake of his collapse at the British the year before.

After he lost the British last year, Scott said it he would learn from the experience. Despite missing again, he said he did.

"I'm happy with my week, other than I didn't win," he said. "But I lived up to my expectations of putting myself in contention with a chance. And it will just have to go down in the experience book and something to build on again."

Source: http://news.yahoo.com/adam-scott-collapses-again-british-open-183944086.html

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Monday, July 15, 2013

Bill Clinton to visit Puerto Rico talk about renewable energy projects

  • Soccernet - Saturday 13th July, 2013

    Chris Wondolowski scored two more goals to raise his total to five in two matches, and the United States came from behind to beat Cuba 4-1 Saturday and advance to the CONCACAF Gold Cup ...

  • Soccer-U.S. beat Cuba to reach Gold Cup quarter-finals

    General Sources - Saturday 13th July, 2013

    July 13 (Reuters) - In-form striker Chris Wondolowski scored twice to steer the United States to a comfortable 4-1 win over Cuba on Saturday and a guaranteed place in the CONCACAF Gold Cup quarter-finals. Wondolowski continued his red-hot form for the American national team with two superbly taken goals in the second half to clinch an expected win after Cuba had grabbed a surprise lead. Jose ...

  • Grenada limits sand mining at 2 beaches to small projects

    Canada.com - Saturday 13th July, 2013

    ST. GEORGE'S, Grenada - The government of Grenada says two beaches it declared open to sand mining will only supply small-scale construction projects such as homes. Works Minister Gregory Bowen said Saturday that major public and private construction projects will be barred from using sand at the Galby and Grand Bacolet areas in the island's rural eastern region. While Grenada banned ...

  • USA v Cuba - live

    The Guardian - Saturday 13th July, 2013

    5 mins First whiff of goal for the US, as a ball gets whipped across the goalmouth for Landon Donovan. Unfortunately, the whistle had already gone for an non-existent foul by Hercules Gomez - penalised for the crime of letting a Cuba defender fall over in front of him after an unsuccessful shoulder ...

  • Holden gets 1st US start in 3 years vs Cuba

    Boston Herald - Saturday 13th July, 2013

    SANDY, Utah - U.S. coach Jurgen Klinsmann made six changes to his starting lineup for Saturday's CONCACAF Gold Cup match against Cuba, giving Stuart Holden his first national team start in nearly three years.Holden had not been in the U.S. first 11 since an exhibition against Colombia on Oct. 12, 2010. A knee injury the following March sustained in a tackle by Manchester United's Jonny ...

  • Bill Clinton to visit Puerto Rico talk about renewable energy projects

    Canada.com - Saturday 13th July, 2013

    SAN JUAN, Puerto Rico - Former President Bill Clinton is scheduled to visit the U.S. territory of Puerto Rico to promote renewable energy projects. Gov. Alejandro Garcia Padilla says Clinton is expected to arrive Monday and talk about ways the island can launch projects through the Clinton Foundation. Puerto Rico is already the planned site of the Caribbean's largest solar energy project, ...

  • Flair v flair in Caribbean face-off

    Cricinfo - Saturday 13th July, 2013

    Test series between the two sides, which leaves them playing out a bunch of ODIs and Twenty20s. What's more, this and the recent tri-series in the Caribbean, which featured India and Sri Lanka, means the only Tests in West Indies' home season were the ones against a rebuilding Zimbabwe. Pakistan are also in a rebuilding phase after some indifferent recent results. The experience of ...

  • Ariel Castro facing 977 charges for abductions of three women

    Middle East Times - Saturday 13th July, 2013

    Ariel Castro has been indicted on 977 counts for allegedly holding three women captive in his Cleveland home. The indictment handed up Friday includes 512 counts of kidnapping, 446 counts of rape, seven counts of sexual abuse, two counts of aggravated murder, six counts of assault, three counts of child endangerment and one count of possessing criminal tools, USA Today reported. The murder ...

  • USA vs Cuba Live Stream Free Soccer Watch Online Gold Cup 2013 CONCACAF Football

    Christian Post - Saturday 13th July, 2013

    USA vs Cuba in the Gold Cup 2013 soccer tournament takes place on Saturday afternoon with the United States looking to build on their confident blowout win against Belize in their opening game. The match will kick off at 3.30 p.m. ET and can be watched online through free live stream (details ...

  • 4 dead 2 injured after bus in Dominican Republic crashes into home

    Canada.com - Saturday 13th July, 2013

    SANTO DOMINGO, Dominican Republic - Four people have died and another two were injured when a bus in the Dominican Republic veered off the road and crashed into a house in the country's eastern region. Transportation Authority spokesman Roberto Lebron says the four people who died were standing outside the house. He said a young boy standing on the sidewalk as well as the bus driver were ...

  • RBC Sponsors Dance Bahamas School ?Masters In Dance Series?

    Bahama Journal - Saturday 13th July, 2013

    RBC Royal Bank recently sponsored the Dance Bahamas School "Masters in Dance Series" program in conjunction with the National Dance Company of The Bahamas. The "Masters in Dance Series" was born out of the realization that there are limited resources locally for dance practitioners and students. The main objective is to enrich the lives of young Bahamians by exposing them to ...

  • Nagico Insurances Officially Launches In The Bahamas

    Bahama Journal - Saturday 13th July, 2013

    Celebratory cheers and glasses raised in a champagne salute is how NAGICO Insurances (Bahamas) Limited ended their official company launch event last Thursday night, June 27, at the Balmoral Club. NAGICO Bahamas is the newest and the 19th Caribbean territory in which NAGICO Insurances operate. Started over 31 years ago in St. Maarten, NAGICO is AM-Best rated and the largest privately-held ...

  • Delayed ambassador appointment ?unusual?

    Nassau Guardian - Saturday 13th July, 2013

    The delayed confirmation of Dr. Elliston Rahming as Bahamas ambassador to the United States is unusual, former Minister of Foreign Affairs Brent Symonette said yesterday. Symonette said the government's silence on the issue is unacceptable. At his office on East Bay Street, he said the delay could be an embarrassment for The Bahamas. "The United States must be, in my humble opinion, ...

  • Govt?s work permit policy ?ill conceived?

    Nassau Guardian - Saturday 13th July, 2013

    The government's plan to cease issuing work permits for maids, housekeepers and laborers within a year is ill conceived, former Foreign Affairs and Immigration Minister Brent Symonette said yesterday. "The issue of not issuing work permits, that sent ramifications around the world," he said. "We have to be careful when we do these things that we don't affect or have ...

  • Workers say they?ve been abandoned by sub-contractor

    Nassau Guardian - Saturday 13th July, 2013

    Scores of laborers working on the Baha Mar development were barred from entering the site yesterday as the sub-contractor was not on site. The laborers claim that they have not been paid for ...

  • Nottage explains plan to redeploy RBDF officers

    Nassau Guardian - Saturday 13th July, 2013

    As the Ministry of National Security finalizes plans for the deployment of 150 Royal Bahamas Defence Force (RBDF) officers to assist police in the crime fight, Minister of National Security Dr. Bernard Nottage is denying claims that the move will leave the Defence Force shorthanded. In the past few weeks, some observers have expressed concern that the Defence Force could not afford to lose any ...

  • Minority groups can be protected through ?ordinary legislation?

    Nassau Guardian - Saturday 13th July, 2013

    The Constitutional Commission chose not to recommend that discrimination based on sexual orientation be declared unconstitutional, instead noting that minority groups can be protected through ordinary legislation. "The commission cannot but note that none of the Caribbean countries, even in the proposed reforms to create new and positive charters, have embraced an inclusion of sexual ...

  • Cuba Backs Nations Offering Snowden Asylum

    CBN News - Saturday 13th July, 2013

    Cuba's president is standing behind the man wanted for leaking information about America's surveillance programs. Raul Castro, 82, is offering support for Venezuela and other Latin American governments willing to give National Security Agency leaker Edward Snowden asylum. "We support the sovereign right of .Venezuela and all states in the region to grant asylum to those ...

  • Video Cleveland kidnapping New charges for Ariel Castro

    CBS News - Saturday 13th July, 2013

    Arield Castro, accused of holding three women captive in his Cleveland home, has been indicted on 977 new charges including kidnapping, rape, and sexual abuse. Castro had already been indicted on more than 300 counts and plead not ...

  • Even sharks are no match for invasive lionfish

    General Sources - Saturday 13th July, 2013

    The invasive lionfish is native to the Indo-Pacific region, though has been eating its way through reefs of the Caribbean Sea and Atlantic Ocean, scientists are finding. With no effective predators, fishing by humans may be the only way to control the population. The eye-catching red lionfish is eating its way through Caribbean reefs, and nothing, not even a toothy shark, seems able to stop the ...

  • Sharks no match for lionfish

    General Sources - Saturday 13th July, 2013

    The invasive lionfish is native to the Indo-Pacific region, though has been eating its way through reefs of the Caribbean Sea and Atlantic Ocean, scientists are finding. With no effective predators, fishing by humans may be the only way to control the population. The eye-catching red lionfish is eating its way through Caribbean reefs, and nothing, not even a toothy shark, seems able to stop the ...

  • Sharks no match for lionfish

    General Sources - Saturday 13th July, 2013

    The invasive lionfish is native to the Indo-Pacific region, though has been eating its way through reefs of the Caribbean Sea and Atlantic Ocean, scientists are finding. With no effective predators, fishing by humans may be the only way to control the population. The eye-catching red lionfish is eating its way through Caribbean reefs, and nothing, not even a toothy shark, seems able to stop the ...

  • Source: http://www.haitinews.net/index.php/sid/215811179/scat/e5abd99746ab67f4

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    Monday, June 24, 2013

    Egypt mob yelled 'infidels' at Shi'ites beaten to death

    By Alexander Dziadosz

    ZAWIYAT ABU MUSALLEM, Egypt (Reuters) - Kasbana Abdelaziz's house guests had barely arrived when the mob was upon them, hurling petrol bombs and smashing holes through the roof of her home.

    The attackers then dragged four men - Shi'ite Muslims who had come to this Cairo suburb for a religious festival - out into the street and beat them to death.

    President Mohamed Mursi condemned the "heinous crime" that happened on Sunday and promised swift justice, but his opponents accuse him and his Muslim Brotherhood of allowing ultraconservative Salafist allies to whip up anti-Shi'ite sentiment in return for their support.

    "They called us infidels," Abdelaziz, said, sitting on her floor amid broken concrete, shattered glass and splintered wood. Two of her daughters stood weeping in the room behind her.

    The mob killing in Zawiyat Abu Musallem has caused outrage among opposition leaders in Egypt at a time of deep political tension in the Arab world's most populous country.

    Little is left of Abdelaziz's house in the Cairo suburb, an area of mud-brick and concrete-block homes, narrow dirt alleyways and fields of date palms in view of the Giza pyramids.

    The kitchen is stripped bare; a battered refrigerator door lies amid dust, scraps of cloth and bricks on the floor. Daylight pours in through holes in the ceiling. An image of the shrine of Imam Ali in Iraq, one of the holiest sites in Shi'ite Islam, hangs on a wall in the ransacked bedroom.

    Abdelaziz had no doubt who was behind the destruction. "It was the Salafists and the Brotherhood - they're the ones who attacked us," she said. "They did things you can't imagine."

    "INFIDELS"

    Shi'ites are a small minority in Egypt - though still number in the hundreds of thousands - and they keep a low profile in the overwhelmingly Sunni country of 84 million. But the war in Syria, which pits mostly Sunni rebels against President Bashar al-Assad and his Shi'ite allies, has worsened sectarian hatreds across the region.

    The violence in Zawiyat Abu Musallem started in the early afternoon, Abdelaziz and her daughters said, just after Hassan Shehata, a Shi'ite dignitary, arrived as a guest of her husband, a plasterer from the area.

    Hundreds of men gathered in the rubbish-strewn alley outside the house when they learned Shehata was inside. "He'd only just entered and come up when we found all the people upon us," Abdelaziz said. "There was chanting - 'you Shi'ites, you infidels'. People were chanting and people were throwing bricks."

    A video posted online showed a crowd dragging four men wearing robes from the house and beating them with fists and rods until they fell, bloodied and motionless, in the alley.

    One comment on the video, which has gained several hundred "likes" on YouTube, addressed Shehata: "May your filthy soul lie in hell forever and ever. Amen."

    Another video posted by rights activists showed dozens of men and youths looking on as several others drag the bloodied body of at least one man along a street, one pulling on what may be a rope around his neck.

    In other sequences, a group of black-robed women on a crowded, narrow street chant "No God but God!" Riot police are present in the video, which shows an officer yelling out in frustration: "They're beating us!"

    Abdelaziz said she did not know what had become of her husband, Farhat, but he may have been taken to hospital after the attack.

    Bahaa Anwar, a leader in Egypt's Shi'ite community, was quoted by state newspaper al-Ahram as saying Mursi and the Brotherhood were using the Shi'ites as a "scapegoat" to appease their Salafist allies.

    Liberal opponents of the Muslim Brotherhood also accused the movement of stirring up sectarian passions by joining in Sunni calls for jihad against Syria's Assad and his Shi'ite allies from Lebanon and Iran.

    Mursi and the Brotherhood angered Salafists by trying to improve relations with Shi'ite Iran after Mursi was elected a year ago but this month the Islamist group threw its weight behind calls for "holy war" against Assad, at a conference in Cairo.

    Mursi's opponents are planning mass rallies on June 30 to call for his resignation and early presidential elections - he and the Brotherhood have staged their own shows of strength, prompting Egypt's army to warn it may step in to impose order.

    (Additional reporting by Maggie Fick, Shaimaa Fayed, Shadia Nasralla and Alastair Macdonald; Editing by Robin Pomeroy)

    Source: http://news.yahoo.com/egypt-mob-yelled-infidels-shiites-beaten-death-163836476.html

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    'Mad Men's' Don Draper boring? Not so fast!

    18 hours ago

    Image: Don Draper

    Carin Baer / AMC

    Don Draper: Dark, mysterious and oh so fascinating!

    When it came time for this season?s Monday morning water-coolering of ?Mad Men,? a common theme erupted nearly every week: ?Don Draper is soooooo boring.?

    Should we interpret the show?s opening of a man falling as Don?s descent into dullsville? The people who feel Don didn?t say enough, feel enough or do enough this season might think so.

    But if you?re part of a very select minority, it?s fair to respond to that notion with a resounding, ?COME ON.?

    While the leading man has been one of few words and has spent many scenes scowling, sneering and often sweating, he?s been less than boring when you consider the sum of the parts.

    Draper, having spent the bulk (if not all) of season five as doting husband to Megan, has finally gone back to his old ways -- cheating ways that is, bedding another woman countless times over the course of season six. But it?s not just any woman he?s taken up with: It?s his neighbor Sylvia Rosen (played so well by Linda Cardellini). Meeting any random woman and taking her back to her place? Boring. Having something resembling a relationship with your neighbor, whose husband is also a friend? Not boring at all.

    And speaking of the ?relationship? between Don and Sylvia, that pretty much hit the skids in another entirely not-boring way. Linda?s husband, Arnold, or Don?s wife, Megan, potentially busting either guilty party was a tension that hung over the entire affair, but in the end it was Sally (poor Sally!) who ended up walking in on Dad ?comforting? their neighbor. Don?s relationship with Sally turns on a dime and changes probably forever. That?s not boring, and did we forget to mention? Neither is the fact that Don hooked up with Betty while they were both visiting Bobby at summer camp.

    Most of these OMG moments did culminate in a sad Don Draper, or at a minimum, a very drunk one, and sure, that?s repetitive and tiresome at times. But in between, viewers also learned more of Don?s childhood this year. (So damaged! So relevant?) Fans witnessed seriously bad behavior (even for Don) at Roger?s mom?s funeral, and was it not fun to watch him make Ken completely flustered all season -- without really even doing much?

    Yes, not doing much is what the ?Don is boring? camp will settle on, but when the season finale airs Sunday, true fans of the show might do right to keep in mind what ?Mad Men? creator Matthew Weiner has done all along each week: His episodes aren?t meant to be snapshots -- they?re all parts of one big story.

    This season?s tale didn?t move along as quickly as others, but that doesn?t make it -- or the main character -- boring. Just more demanding.

    Source: http://www.today.com/entertainment/mad-mens-don-draper-boring-not-so-fast-6C10411622

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    Court says no to generic drug design lawsuits

    (AP) ? The Supreme Court says generic drug manufacturers can't be sued in state court for a drug's design defects if federal officials approved the brand-name version the generic drug copied.

    The justices voted 5-4 to agree with generic manufacturer Mutual Pharmaceutical Co, Inc., which wanted a $21 million judgment against it dismissed.

    A New Hampshire jury gave that to Karen L. Bartlett after she took sulindac, the generic form of the drug Clinoril, in 2004. It caused her outer skin layer to deteriorate and burn off, leaving at least 60 percent of her body as an open wound. She is also now legally blind.

    The federal appeals courts upheld her verdict, but the justices said federal law pre-empts the New Hampshire law that allowed Bartlett's lawsuit.

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-06-24-Supreme%20Court-Generic%20Drugs/id-764427aabda64ff5bea64cab1bd85803

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    Tuesday, June 11, 2013

    Background mortality rates key to accurate reporting of vaccine safety risks

    June 11, 2013 ? In a study using the Vaccine Safety Datalink (VSD), investigators analyzed four years of data and determined that background mortality rates (rates of death irrespective of cause) are crucial in interpreting the numbers of deaths following vaccination. The VSD mortality rate following immunization is lower than the general US population mortality rate, and the causes of death are similar. These background rates can be used in communications to the public about vaccine safety risks, reports the American Journal of Preventive Medicine.

    Public concern about deaths and other adverse events following immunization can disrupt immunization programs and lead to an increase in vaccine-preventable disease.

    "Determining the baseline mortality rate in a vaccinated population is necessary to be able to identify any unusual increases in deaths following vaccine administration," says lead investigator Natalie L. McCarthy, MPH, an epidemiologist at the Centers for Disease Control and Prevention (CDC). VSD mortality rates demonstrate a healthy vaccinee effect where rates were lowest in the days immediately following vaccination, most apparent in the older age groups. The healthy vaccinee effect suggests an avoidance or delay of vaccination when an individual is sick, leading to lower background rates of illness or mortality immediately following vaccination.

    "Although there is currently no evidence to support a causal relationship between vaccinations and death, this study provides background mortality rates following vaccination to be used as a baseline when examining the safety profiles of new vaccines and during mass immunization campaigns," adds McCarthy.

    Investigators from the Centers for Disease Control and Prevention (CDC) and ten healthcare organizations (sites) that conduct vaccine safety research and surveillance, report on background mortality rates, describe causes of death following vaccination, and examine mortality rates by age, gender, and number of days following vaccination using data recorded in the Vaccine Safety Datalink (VSD).

    The VSD is a collaborative project between the CDC and these sites and captures comprehensive medical and immunization histories for over ten million people annually, or approximately three percent of the US population. It uses administrative and other sources at each site to gather data on enrollee demographics, vaccination, and medical outcomes, including mortality. The VSD conducts planned immunization safety studies following the introduction of new vaccines or changes in the immunization schedule, as well as timely investigations of hypotheses that arise from review of medical literature, clinical case reports, or reports from the Vaccine Adverse Event Reporting System (VAERS), a national passive adverse-event reporting system.

    Analyses were conducted in 2012. Mortality rates were calculated for deaths occurring one, seven, 30 and 60 days following vaccination between January 1, 2005 and December 31, 2008. The analyses were stratified by age and sex. Causes of death were examined, and findings were compared with National Center for Health Statistics (NCHS) data.

    Among 13,033,274 vaccinated people, 15,455 deaths occurred within 60 days following vaccination. The rates were highest in people of age 85 years and older, and increased over the period following vaccination. Eleven of the 15 leading causes of death in the VSD and NCHS overlap in both systems, and the top four causes of death were the same in both systems.

    This study was supported by the Vaccine Safety Datalink contract with America's Health Insurance Plans, funded by the CDC. "The Vaccine Safety Datalink provides a vital infrastructure for monitoring vaccine safety, and generating background mortality rates is another asset of the vaccine safety system. Similar analyses should be conducted when new vaccines are added to the CDC's Advisory Committee on Immunization Practices recommended schedule, and would also be useful in other populations, including vulnerable subpopulations such as pregnant women and people with underlying health conditions," says McCarthy.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/v-jm1QidAnU/130611102032.htm

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    Friday, May 17, 2013

    Lawmakers accuse IRS officials of lying in tax scandal

    By Andy Sullivan and Kim Dixon

    WASHINGTON (Reuters) - Lawmakers accused leaders of the Internal Revenue Service of lying on Friday as they opened the first in a series of investigative hearings about the tax collection agency's targeting of conservative groups.

    Republicans and Democrats said senior IRS officials should have alerted Congress last year when they found out that their examiners were singling out Tea Party groups for intense scrutiny when the groups applied for tax-exempt status.

    "That isn't being misled. That's lying," said Republican Dave Camp, the chairman of the House of Representatives Ways and Means Committee.

    The acting head of the agency, Steven Miller, apologized for the IRS's actions and said they stemmed from poor management, rather than a partisan desire to punish conservative groups.

    "I did not mislead Congress or the American people," said Miller, who was fired by President Barack Obama on Wednesday. "I think what happened here is that foolish mistakes were made by people trying to be more efficient."

    Obama, a Democrat, is racing to get in front of a scandal that threatens to eclipse his second-term agenda. He has twice appeared in public to condemn the IRS's actions and has promised to cooperate with three congressional investigations and a Justice Department probe. He has, however, resisted demands for a special prosecutor to look into the allegations.

    Republicans have angrily accused Obama's administration of using government powers to target political foes. They say the IRS scandal is one example of a federal government that has grown too large and intrusive.

    "Is this still America?" asked Republican Representative Kevin Brady of Texas.

    AN EXPLOSION OF ADVOCACY GROUPS

    An internal IRS watchdog reported this week that IRS investigators had singled out groups that had conservative-sounding phrases such as "Patriot" and "Tea Party" in their titles when they applied for a tax-exempt status.

    Such status allows groups to keep their donor lists secret while engaging in limited political activity. Political campaigns, by contrast, must make their donors lists public.

    Tea Party groups say they were asked for information such as what books they read. The questioning in some cases took nearly three years, preventing certain groups from participating in the 2010 and 2012 elections.

    The IRS watchdog blamed the scandal on ineffective management and bureaucratic confusion.

    The IRS has seen the number of groups applying for so-called 501(c)4 status double in the wake of a January 2010 Supreme Court decision that loosened campaign-finance rules at a time when it has struggled to monitor existing tax-exempt groups.

    The top Democrat on the committee, Representative Sander Levin, warned Republicans not to turn the investigation into a partisan witch hunt.

    However, he noted that Lois Lerner, the IRS official who made the scandal public last week, did not bring it up when she testified in front of the committee a few days earlier.

    "That is wholly unacceptable and one of the reasons we believe Miss Lerner should be relieved of her duty," Levin said.

    Two other committees, the House Oversight and Government Reform Committee and the Senate Finance Committee, also will hold IRS hearings next week.

    (Additional reporting by Patrick Temple-West and Susan Heavey; Editing by David Lindsey and Jackie Frank)

    Source: http://news.yahoo.com/obama-picks-temporary-irs-head-tea-party-decries-003205741.html

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    Tuesday, March 5, 2013

    Bobby Rogers of The Miracles dies at age 73

    By The Associated Press

    Fred Prouser / Reuters file

    Bobby Rogers, a founding member of the Miracles singing group with Smokey Robinson, died on March 3.

    SOUTHFIELD, Mich. --?Bobby Rogers, a founding member of Motown group The Miracles and a songwriting collaborator with Smokey Robinson, died Sunday at his suburban Detroit home. He was 73.?

    Motown Museum board member Allen Rawls said Rogers died about 6 a.m. in Southfield. Rogers had been ill for several years.

    Rogers formed the group in 1956 with cousin Claudette Rogers, Pete Moore, Ronnie White and Robinson. Their hits included "Shop Around," "You've Really Got a Hold on Me," "The Tracks of My Tears," "Going to a Go-Go," "I Second That Emotion" and "The Tears of a Clown."

    "Another soldier in my life has fallen. Bobby Rogers was my brother and a really good friend," Robinson said Sunday in a statement. "He and I were born on the exact same day in the same hospital in Detroit. I am really going to miss him. I loved him very much."

    Rogers' cousin Claudette told the Detroit Free Press that everyone was drawn to his personality.

    "People always commented on the tall one with the glasses," she said. "He was personable, approachable and he loved talking to the women, loved talking to the guys, loved to dance, loved to sing, loved to perform. That was the joy of his life."

    His voice can be heard on Marvin Gaye's "What's Going On," with Rogers saying, "It's just a groovy party, man, I can dig it." Mary Wilson of the Supremes said that captured his essence.

    "If people want to remember him, they should put that record on and listen to Bobby," Wilson told the newspaper. "That's who he was."

    Rogers and The Miracles were inducted into the Rock and Roll Hall of Fame in 2012. He was too ill to attend the ceremony.

    He shared songwriting credits with Robinson on The Temptations' "The Way You Do the Things You Do," The Contours' "First I Look at the Purse" and The Miracles' "Going to a Go-Go."

    Funeral arrangements through James H. Cole Home for Funerals in Detroit were incomplete Sunday afternoon.?

    More in Entertainment:

    Source: http://todayentertainment.today.com/_news/2013/03/03/17172759-bobby-rogers-of-motown-group-the-miracles-dies-at-age-73?lite

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    Friday, February 15, 2013

    Amanda Bynes' Weird Behavior Reaching Legendary Status

    Source: http://www.thehollywoodgossip.com/2013/02/amanda-bynes-weird-behavior-reaching-legendary-status/

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    Washington Real Estate Investment Trust (WRE) Posts Quarterly Earnings, Beats Expectations By $0.01 EPS

    Washington Real Estate Investment Trust (NYSE: WRE) announced its earnings results on Wednesday. The company reported $0.47 earnings per share (EPS) for the quarter, beating the consensus estimate of $0.46 by $0.01. The company had revenue of $77.07 million for the quarter, compared to the consensus estimate of $76.52 million. During the same quarter in the previous year, the company posted $0.47 earnings per share. The company?s revenue for the quarter was up 2.2% on a year-over-year basis.

    On the ratings front, analysts at Robert W. Baird initiated coverage on shares of Washington Real Estate Investment Trust in a research note to investors on Monday, January 14th. They set a ?neutral? rating and a $29.00 price target on the stock.

    Shares of Washington Real Estate Investment Trust (WRE) traded down 0.43% during mid-day trading on Wednesday, hitting $27.98. Washington Real Estate Investment Trust (WRE) has a 52 week low of $23.94 and a 52 week high of $30.51. The stock?s 50-day moving average is currently $27.45. The company has a market cap of $1.856 billion and a P/E ratio of 36.88.

    The company also recently announced a quarterly dividend, which is scheduled for Friday, March 29th. Shareholders of record on Friday, March 15th will be paid a dividend of $0.30 per share. This represents a $1.20 annualized dividend and a dividend yield of 4.29%.

    Washington Real Estate Investment Trust (WRIT) is a self-administered, self-managed, equity real estate investment trust (REIT).

    Keep up with the latest quarterly earnings announcements by subscribing to our daily earnings update. With your free subscription, you will receive a concise daily summary of corporate earnings announcements. Click here to subscribe.

    Source: http://www.jagsreport.com/2013/02/washington-real-estate-investment-trust-wre-posts-quarterly-earnings-beats-expectations-by-0-01-eps/

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    Actors' Union And Advertisers Are Negotiating $1 ... - Business Insider

    The talks cover actresses like Kaley Cuoco, who just started appearing in ads for brands like Priceline.

    SAG-AFTRA and the advertising industry are launching commercial contract talks on Valentine's Day under a cone of silence with a minimal disclosure of details -- offering a vivid contrast to the six-month strike that crippled the blurb biz 13 years ago.

    It's the first major contract to come up for renewal by SAG-AFTRA since members approved merging SAG and AFTRA last March following a robust campaign that promised more bargaining power.

    Both sides declined to comment on the talks, which will take place in Gotham. The current contract, which covers roughly $1 billion in annual earnings, expires on March 31 but the union has made no efforts to mobilize the members about the issues.

    And that's a step that would be expected if SAG-AFTRA were to seek a strike authorization vote, as was done in 2000 amid a pledge by the ad industry to not sign a deal unless the pay-per-play system of compensation, known as "Class A," was replaced by quarterly buyouts. Both sides posted their entire bargaining proposal on the Internet; during the strike, SAG and AFTRA held hundreds of rallies and pickets, culminating in a boycott of Ivory Soap, Tide and Crest before getting a deal that preserved Class A, boosted cable pay by 140% and gave the union jurisdiction over Internet ads.

    "Educating the members was critical back then," said Gordon Drake, a strike captain and negotiating committee member in 2000. "We felt that members needed to feel they were part of the union so we were able to hold out for that deal. So I completely disagree with the approach that SAG-AFTRA is taking to this negotiation."

    The strike came following the election of William Daniels as SAG president in 1999 over incumbent Richard Masur in a campaign that promised a far more aggressive bargaining stance. After negotiations cratered, the SAG and AFTRA boards voted 150-0 to go on strike -- a show of unity that began dissipating as the strike went on, particularly among members outside Hollywood who contended in the aftermath that settlement's terms had been achievable without a strike.

    In recent years, the self-styled moderates within SAG have taken over the leadership of the union in elections by pushing hard for merger and largely avoiding public confrontation with employers. SAG-AFTRA's only recent disclosure about the commercial negotiations came Feb. 3 after its national board gave its blessing to the package of proposals, hammered out via the "wages and working conditions" member meetings in recent months.

    That announcement had no elaboration of the package, however. David White, the union's national exec director and chief negotiator, said, "While there are difficult issues to negotiate ahead, we anticipate a productive dialogue with our bargaining partners and expect a result that is positive for our members." SAG-AFTRA co-president Roberta Reardon told Variety last month the merger would have an impact on all of the union's successor contracts. "So it's going to be a year where we discover that solidarity, power and leverage are not just words. And the consolidation within the media industry will have a huge impact on these contracts," she said.

    For its part, the ad industry -- repped through the joint policy committee of the American Assn. of Advertising Agencies and the Assn. of National Advertisers -- has broached the possibility of a strike.

    The committee told members in December to consider "prudent planning" in the case of a strike including rescheduling production planned for March 31 through June. It also advised members to consider taking steps to maintain rights on current commercials if those rights are expiring in the three months after March 31.

    The union and the industry are in the final seven weeks of a one-year extension to the three-year contract reached in 2009. SAG and AFTRA sought and received the extension in mid-2011 in order to focus their efforts on a merger. The key gains in the current commercials contract included a payment structure for work made for and moved over to the Internet and other new-media platforms and retention of the Class A method of pay-per-play.

    The 2009 deal yielded a $36 million pay hike over three years, including $21 million more in pension and health contribution and held down annual salary gains to about 2% and included a first-ever cap on employer contributions to pension and health.

    Drake still believes that SAG-AFTRA leaders needs to tell members more about contract details heading into negotiations and cites his own experience two decades ago while rehearsing for a dance scene with Annette Bening in "Bugsy." "I told her that I didn't have a SAG contract, so she told the production assistant to get me one," he recalled. "That didn't happen because of the leaders but because of a member."

    Click here for more film news on Variety.com.

    Source: http://www.businessinsider.com/actors-union-and-advertisers-are-negotiating-1-billion-in-fees-and-some-expect-a-strike-2013-2

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    Merck settles investor suits on cholesterol drugs

    (AP) ? Merck & Co. has agreed to pay $688 million to settle two long-running lawsuits brought by investors who alleged the drugmaker delayed releasing bad news on its blockbuster cholesterol drugs to prevent a drop in sales.

    Merck, the world's third biggest drugmaker by revenue, said Thursday that it agreed to the settlement because it's in the best interest of the company and current shareholders. It is taking a charge of nearly a half-billion dollars against 2012 earnings.

    The delay in releasing results of a study that was meant to bolster sales of pricey cholesterol pills Zetia and Vytorin triggered criticism by analysts, investors, some scientists and the media ? and ultimately an investigation by Congress.

    The maker of Januvia Type 2 diabetes pills and the Gardasil vaccine against sexually transmitted cancers admitted no wrongdoing. The deal must be approved by a federal judge.

    "The settlement gets a cloud out of the sky for Merck," said Erik Gordon, an analyst and professor at University of Michigan's Ross School of Business.

    The settlement is among the top 25 securities class action settlements ever, according to Bernstein Litowitz Berger & Grossmann LLP, co-lead counsel in the litigation brought by a number of large pension funds.

    Merck, which is based in Whitehouse Station, N.J., said in a statement that it's taking a charge of $493 million. The company also restated previously reported financial results, reducing its 2012 fourth-quarter results to 30 cents per share from 46 cents per share, and its 2012 results to $2 per share from $2.16 per share.

    Merck shares fell 13 cents to $41.02 in afternoon trading. They have traded in a 52-week range of $36.91 last March to $48 in mid-October.

    Merck and its then-partner Schering-Plough, which it later acquired, for about two years had delayed disclosing results of the study, known by the acronym ENHANCE. It tested how well Vytorin and Zetia reduced plaque buildup in neck arteries of patients with high cholesterol. The drugs had already been on the market for a few years, and together generated billions in annual sales for the two New Jersey drugmakers, racking up a combined $5.2 billion in 2007 alone.

    The study was intended to give the pills a bigger edge over rival medicines in the huge market for cholesterol drugs, by showing that besides reducing bad, or LDL cholesterol, the pills prevented it from clogging arteries ? and presumably from causing heart attacks and strokes. But imaging of neck arteries of ENHANCE study participants showed that Zetia and Vytorin, which combines Zetia with a generic version of Merck's older cholesterol pill Zocor, didn't work any better than cheap generic Zocor did alone.

    When Merck in early 2008 finally released the ENHANCE study results, Merck stock tumbled, causing big losses for investors, and sales of the two pills declined in the U.S.

    Bernstein Litowitz, Grant & Eisenhofer and other law firms representing pension funds in the U.S. and elsewhere that held Merck and Schering-Plough stock then filed suits against each of the companies. Under the settlement agreement, Schering-Plough, which became part of Merck in 2009, will pay $473 million, and Merck will pay $215 million. A Merck spokesman said the company expects insurance to cover part of the total, reducing Merck's liability to the $493 million for which it's taking a charge.

    Edward Jones analyst Judson Clark said the settlement is "largely a non-issue for long-term equity investors."

    However, he added, "The combined number was probably a little higher than many investors were expecting and that's reflected in today's price movement."

    Merck said in a statement that "numerous clinical trials conducted over the years have demonstrated a strong relationship between lowering LDL cholesterol and reduced risk of cardiovascular morbidity and mortality."

    It added that its ongoing IMPROVE-IT study, an 18,000-patient study of Vytorin, should answer the question of whether lowering LDL cholesterol to very low levels with Vytorin could reduce heart attacks and strokes more than generic Zocor alone could do.

    However, during a conference call two weeks ago to review fourth-quarter results, Merck executives would not reassure nervous analysts that the IMPROVE-IT study will show that benefit. Merck stressed then that it has numerous drugs in late-stage development and plans this year to file for approval of five of them. Still, two analysts quickly downgraded their ratings on its shares, one from "Hold" to "Sell" and the other from "Buy" to "Hold."

    Analyst Les Funtleyder, a health care strategist at private equity fund Poliwogg, said the settlement news "will get lost in concern over" Merck saying recently that it will delay for about a year plans to apply for approval of a crucial new osteoporosis drug, odanacatib, while it waits for additional study results.

    The settlement comes less than three weeks before the case was to come to trial. It had been scheduled to begin on March 4, before U.S. District Judge Dennis M. Cavanaugh in Newark, who must approve the settlement.

    ______

    Linda A. Johnson can be followed at http://twitter.com/LindaJ_onPharma

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-02-14-Merck-Cholesterol%20Drug%20Suit/id-5236be8cf897431a9bfb698cfca04d88

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    Thursday, February 14, 2013

    Inorganic Growth ? Corsair acquires streaming audio systems ...

    Posted by Tejas Venkatesh on February 13, 2013

    Contact: Tejas Venkatesh

    Its IPO plans may not have materialized, but high-performance hardware designer Corsair is continuing to add to its product capabilities. In its first-ever acquisition, Corsair has reached for Simple Audio, a maker of streaming systems that enable consumers to remotely listen to music stored on computers and mobile devices. With audio being an integral part of gaming, the deal adds complementary audio products to Corsair?s stable of headsets, speakers and memory modules.

    Corsair should also be able to use its worldwide distribution channels to drive sales of Simple Audio?s products. Terms of the transaction were not disclosed but the target described it as a ?multimillion-dollar? deal. According to a press release from Young Company Finance, which tracks and reports on early-stage high-growth companies in Scotland, Simple Audio generated about $2.1m in revenue for the nine months ended September 2012. The company only started selling its products in January 2012.

    Corsair designs high-performance DRAM modules and other gaming peripherals for personal computers, with a focus on gaming hardware. The low-margin DRAM business accounts for more than two-thirds of its revenue. The company was on track for an IPO before pulling its paperwork in May 2012, citing poor market conditions. For the year ended March 2012, Corsair generated a top line of $480m, with a gross margin in the mid-teens.

    For more real-time information on tech M&A, follow us on Twitter @MAKnowledgebase.

    Filed Under Digital music, investment banking, M&A, storage, technology stocks | Leave a Comment

    Comments

    Source: http://blogs.the451group.com/techdeals/storage/corsair-acquires-streaming-audio-systems-provider-simple-audio/

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    Emmett Till's family reacts to Lil Wayne lyric

    FILE - In this Sept. 26, 2012 file photo, recording artist Lil Wayne speaks during an interview with The Associated Press in New Orleans. Epic Records is going to "great efforts" to take down a new Future remix leaked over the weekend with a vulgar lyric by Lil Wayne that has offended the family of Emmett Till. (AP Photo/Gerald Herbert, File)

    FILE - In this Sept. 26, 2012 file photo, recording artist Lil Wayne speaks during an interview with The Associated Press in New Orleans. Epic Records is going to "great efforts" to take down a new Future remix leaked over the weekend with a vulgar lyric by Lil Wayne that has offended the family of Emmett Till. (AP Photo/Gerald Herbert, File)

    FILE - This undated file photo shows Emmett Till, a black 14-year-old Chicago boy, who was brutally murdered near Money, Mississippi, Aug. 31, 1955, after whistling at a white woman. Epic Records is going to "great efforts" to take down a new Future remix leaked over the weekend with a vulgar lyric by Lil Wayne that has offended the family of Emmett Till. (AP Photo/File)

    (AP) ? A cousin of the late Emmett Till wonders if Lil Wayne understands just how damaging it was when he rapped a vulgar reference to the black U.S. teen whose death in 1955 became a significant moment in the civil rights movement.

    Airickca Gordon-Taylor says Till's family would like an apology from Lil Wayne for the brief but disturbing lyric on Future's "Karate Chop" remix. But more than that, she'd like the platinum-selling New Orleans rapper to understand how his comparison of a sex act to the 14-year-old Chicago native's torture death in Mississippi is hurtful to the black community.

    "It was a heinous murder," Gordon-Taylor said in a phone interview Thursday from Chicago. "He was brutally beaten and tortured, and he was shot, wrapped in barbed wire and tossed in the Tallahatchie River. The images that we're fortunate to have (of his open casket) that 'Jet' published, they demonstrate the ugliness of racism. So to compare a woman's anatomy ? the gateway of life ? to the ugly face of death, it just destroyed me. And then I had to call the elders in my family and explain to them before they heard it from some another source."

    The Future remix with Weezy guesting was leaked on the internet over the weekend. Epic Records said Wednesday it regretted the unauthorized remix version and that it was employing "great efforts" to pull it down. The brief reference ? just seven words ? will be stricken from the song when it's officially released later.

    The rapper made a crude reference to rough sex and used an obscenity. He indicated he wanted to do as much damage as had been done to Till.

    Gordon-Taylor says Epic Chairman and CEO LA Reid personally reached out to her on a conference call Wednesday evening that included the Rev. Jesse Jackson to explain and apologize. Jackson said in a phone interview Thursday that Reid said on the call that Future and Lil Wayne were cooperative.

    "Once he got the point he realized this was beyond the zone and he immediately pulled it," Jackson said. "And he talked with both artists, who agreed."

    Weezy has made no comment, nor has he addressed the issue on his Twitter account. Gordon-Taylor says there's been no attempt to apologize so far.

    Till was in Mississippi visiting family when he was killed for flirting with a white woman. He was beaten, had his eyes gouged out and was shot in the head before his assailants tied a cotton gin fan to his body with barbed wire and tossed his body into the Tallahatchie River. Two white men, including the woman's husband, were acquitted of the killing by an all-white jury.

    Till's body was recovered and returned to Chicago where his mother, Mamie Till, insisted on having an open casket at his funeral. The pictures of his battered body helped push civil rights into the cultural conversation in the U.S. Bob Dylan even wrote a song about it: "The Death of Emmett Till."

    Gordon-Taylor, founding director of the Mamie Till Mobley Memorial Foundation, said Lil Wayne's lyric was devastating to her family. Simeon Wright, Till's cousin who shared a bed with his relative the night he was taken by the killers, heard the lyric for the first time Wednesday night.

    "And he said the Ku Klux Klan would be very proud of Lil Wayne," Gordon-Taylor said. "And as tough a man as he is, I could see the hurt and the anger in his eyes. It just demonstrates to our family just how lost are our youth."

    Both Gordon-Taylor and Jackson believe the 30-year-old rapper could help with that problem if he chose. Jackson says he's met Wayne, whose real name is Dwayne Carter, before and that he "respects his art."

    Jackson says the issue of a negative portrayal of the black community comes up from time to time, citing The Rolling Stones' "Some Girls," for instance: "We just felt they could make their point without grossly insulting people."

    Music also has the power to uplift, he noted. Harry Belafonte opened eyes to conditions in Africa and the Caribbean, for instance. Marvin Gaye's "What's Going On" helped Americans see the war in Vietnam in a new light. And Stevie Wonder's "Happy Birthday" helped clear the way for a national holiday honoring Dr. Martin Luther King Jr.

    "We want artists who have considerable power to use their power to uplift and redirect," Jackson said. "It's not a matter of free speech, it's also speech that matters. ... These artists have culturally transforming power. Either they hurt or they help."

    ___

    Online:

    http://epicrecords.com

    ___

    Follow AP Music Writer Chris Talbott: http://twitter.com/Chris_Talbott

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-02-14-People-Lil%20Wayne/id-7f56cca9fe6a47c39eb1404834280061

    iOS 6.1

    A little molecule's remarkable feat: Prolonging life

    Feb. 14, 2013 ? Nitric oxide, the versatile gas that helps increase blood flow, transmit nerve signals, and regulate immune function, appears to perform one more biological feat -- prolonging the life of an organism and fortifying it against environmental stress, according to a new study.

    The study reveals that a roundworm called Caenorhabditis elegans, an animal widely used in laboratory studies of aging, lives significantly longer when fed bacteria capable of manufacturing nitric oxide. The tantalizing observation points to one of the mechanisms by which the microbiome, the trillions of microbial cells inhabiting our bodies, may play a vital role in our health.

    Our own nitric oxide levels decrease as we get older, a decline that may contribute to normal aging, says Evgeny Nudler, PhD, the Julie Wilson Anderson Professor of Biochemistry at NYU Langone Medical Center, who led the new study. Supplemental bacteria, he speculates, might provide a healthy boost by supplying humans with some of the missing compound.

    "In worms, we now know that bacteria can use nitric oxide not only to their own advantage but also to provide their host with a beneficial response, and the same thing could be true in a human gut," says Dr. Nudler. "It may well be the case that our commensal bacteria control some of our genes, at least in the gut, to protect those cells against stress and age-related decline." Commensal bacteria provide a benefit to the organisms they colonize.

    Although humans and many other organisms have the enzyme needed to produce nitric oxide, C. elegans does not. Instead, Dr. Nudler and his team report in the February 14th online issue of Cell that the worm can "hijack" the compound from the soil-dwelling Bacillus subtilis bacterium that is not only a favored food but also a common colonist within its gut. This resourcefulness, Dr. Nudler says, partially explains why worms fed B. subtilis live roughly 50 percent longer than counterparts fed Escherichia coli, which does not produce the compound.

    In the new study, the average C. elegans lifespan increased by nearly 15 percent, to about two weeks, when researchers fed the worms nitric oxide-producing B. subtilis bacteria, compared to worms fed mutant B. subtilis with a deleted nitric oxide production gene. The research group also used fluorescent sensors to show that C. elegans does not make its own nitric oxide gas. When the worms were fed normal B. subtilis bacteria, however, the fluorescent signal appeared in their guts.

    Fluorescent labeling and other tests also demonstrated that B. subtilis-derived nitric oxide penetrated the worms' tissues, where it activated a set of 65 genes. Some had been previously implicated in stress resistance, immune response, and increased lifespan, though others have unknown functions. Importantly, the researchers showed that two well-known regulatory proteins were essential for activating all of the genes.

    "What we found is that nitric oxide gas produced in bacteria inside the worms diffuses into the worm tissue and activates a very specific set of genes acting through two master regulators, hsf-1 and daf-16, resulting in a high resistance to stress and a longer life," Dr. Nudler says. "It's striking that a small molecule produced by one organism can dramatically affect the physiology and even lifespan of another organism through direct cell signaling."

    As part of nitric oxide's expansive repertoire, Dr. Nudler's lab previously showed how dangerous pathogens can exploit the molecule to fight off antibiotics. Despite its versatility, the new research suggests that nitric oxide is only one of multiple beneficial molecules produced by B. subtilis, Dr. Nudler says. His lab plans to look more closely at other potential mechanisms by which commensal bacteria can promote health and longevity, using the powerful and easily manipulated C. elegans system as a model.

    The study co-authors include Ivan Gusarov, Laurent Gautier, Olga Smolentseva, and Ilya Shamovsky from the Department of Biochemistry and Molecular Pharmacology at NYU Langone Medical Center; and Svetlana Eremina and Alexander Mironov from the State Research Institute of Genetics and Selection of Industrial Microorganisms in Moscow, Russia.

    The research was supported by the National Institutes of Health, the Biogerontology Research Foundation, and the Dynasty Foundation.

    Share this story on Facebook, Twitter, and Google:

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    Story Source:

    The above story is reprinted from materials provided by NYU Langone Medical Center, via Newswise.

    Note: Materials may be edited for content and length. For further information, please contact the source cited above.


    Journal Reference:

    1. Ivan Gusarov, Laurent Gautier, Olga Smolentseva, Ilya Shamovsky, Svetlana Eremina, Alexander Mironov, Evgeny Nudler. Bacterial Nitric Oxide Extends the Lifespan of C. elegans. 14 February 2013, Cell DOI: 10.1016/j.cell.2012.12.043

    Note: If no author is given, the source is cited instead.

    Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/ibVgvxDP1_4/130214132623.htm

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    Asian Gaming Giant Nexon Sees Revenues Climb 39% To $331.4M ...

    Nexon, the freemium gaming company that went public around the time that Zynga did, saw its fourth-quarter revenues jump 39 percent to 30.9 billion Japanese yen ($331.4 million).

    It still posted a net loss of 94 million yen ($1 million) because of writedowns in various investments and higher tax expenses in South Korea.

    Founded in Seoul almost 20 years ago, Nexon built a strong business in downloadable PC games in China and South Korea with franchises like MapleStory, which have done more than $1 billion in cumulative revenue. The company later moved its headquarters to Tokyo, and?raised $1.2 billion in a late 2011 IPO.

    While the company?s stock hasn?t done as badly as Zynga?s over the past year, it hasn?t been easy either. Nexon?s shares trade 29 percent lower than they did a year ago, as gaming stocks like GREE and others globally have struggled.

    The business? operating margins declined slightly into this last quarter because the company?s growing line of mobile games have lower profit margins than Nexon?s downloadable game business in China. The company?s shares declined 3.4 percent today to 857 Japanese yen ($9.20).

    Nexon expects that its PC business will be roughly flat this quarter at between $305.9 million and $324.4 million in revenue. But mobile games will have grown by more than thirty-fold year-over-year at between $79.4 million and $87.4 million in revenue.

    That?s off the back of two key mobile acquisitions over the past year, including the $468.4 million deal to buy top Japanese game developer gloops. gloops is one of the top developers on DeNA?s Mobage platform. Both DeNA and Nexon recently affirmed a gaming partnership that would bring about 10 different Nexon and gloops-produced games to the Mobage platform this year.

    Nexon also bought another studio called InBlue in mid-2012, but terms weren?t disclosed.

    Screen Shot 2013-02-13 at 12.54.23 PM


    Innovation. That?s what Nexon is all about. A pioneer in the world of interactive entertainment software, they introduced the world to the first graphic MMORPG, The Kingdom of the Winds, back in 1995. Since then, they?ve become the industry leader in massively multiplayer online games, continuing to redefine the genre with each of their innovative titles.

    ? Learn more

    Source: http://techcrunch.com/2013/02/13/nexon-revenues-q4/

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    Saturday, February 9, 2013

    HP sets labor guidelines in for Chinese suppliers

    (AP) ? Hewlett-Packard Co., the world's largest personal computer maker, is vowing to crack down on its Chinese suppliers in an effort to reduce the use of low-paid student interns and other temporary workers.

    The guidelines unveiled Friday are the latest attempt by a major U.S. technology company to weed out labor abuses at Chinese factories that manufacture the gadgets for an Internet-connected world.

    HP, which is based in Palo Alto, Calif., said its new standards are meant to ensure that its Chinese suppliers don't lean too heavily on student interns and temporary workers as a way to save money. The company says it wants to protect workers' rights when they are hired.

    The new standards come a few months after Hon Hai Precision Industry Co., a major China manufacturer better known as Foxconn, acknowledged it has hired interns as young as 14.

    Both HP and Apple Inc., the maker of iPhones, iPads and Mac computers, rely on Foxconn to make some of their products.

    Apple, which is based in Cupertino, Calif., also has been trying to reform the labor practices at Foxconn and other Chinese suppliers in recent years in response to scathing criticism about the inhumane treatment of the workers making devices that have become status symbols as well as multi-purpose tools for communicating, reading, watching video and taking pictures.

    Among other things, HP said it hopes its rules will prod its Chinese suppliers to employ mostly full-time workers instead of exploiting interns and temporary employees. When interns and temps are used, HP said it will insist they aren't forced to remain on the job against their will and have the right to file grievances. The company also pledged to ensure intern hours are kept well below the legal limit.

    To show it is serious, HP intends to review the labor practices at its Chinese suppliers more frequently.

    HP is a Silicon Valley pioneer whose late founders, William Hewlett and David Packard, become renowned for their egalitarian policies and generous benefits. The worker-friendly culture that they fostered become known as "The HP Way" ? a template that has steered the views of many other Silicon Valley companies, including Apple, whose late founder, Steve Jobs, once briefly worked at HP.

    In recent years, though, HP has alienated some of its 332,000 employees with mass layoffs and other cost-cutting measures aimed at boosting its profits. The company eliminated nearly 18,000 jobs during its past fiscal year.

    HP's stock gained 41 cents, or 2. 5 percent, to $16.85 in afternoon trading Friday. They have traded in a 52-week range of $11.35 to $30.

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-02-08-US-HP-China-Suppliers/id-75ebd90908cd461c989a8959aeb0b814

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    Anti self-immolation propaganda now part of China's 'patriotic ...

    After engaging in severe and systematic crackdown on self-immolation protests last year, the Chinese government has now stepped up the ante on propaganda offensive by conducting ?patriotic education? campaigns heavily centred on anti self-immolation messages and distribution of campaign paraphernalia such as documents, pamphlets, books, and animated posters exhorting the Tibetans both in pictures and words, the criminal consequences such as arrests, detention, and heavy prison terms including suspended death sentence.

    According to information received by TCHRD, the Chinese government has published a document, targeted at Tibetans, that explains the legal consequences under Chinese Criminal Law for anyone charged of inciting, instigating or abetting self-immolations. The document, probably a booklet, dated January 2013, is titled ?Cherish Life, Abide by Law.?

    Front cover of the pamphlet titled "Cherish life, Abide by Law."

    Front cover of the pamphlet titled ?Cherish life, Abide by Law.?

    Sources with contacts in Rebkong told TCHRD that the pamphlets were distributed in all monastic institutions, villages and townships in Rebkong (Ch: Tongren) County in Malho (Ch: Huangnan) Tibetan Autonomous Prefecture, Qinghai Province.

    Reports have also emerged on Chinese authorities conducting ?patriotic education? campaign at Jhakyung Monastery in Palung County of Tsoshar (Ch: Haidong) Prefecture, Qinghai Province. Teachers from Qinghai minority Nationality University and Qinghai Teacher Training School were sent to the monastery to give political education sessions which contained strong messages against self-immolation, reported the Voice of Tibet radio. Citing a source in the area, the report said ?patriotic education? officials emphasised the usual patriotic lessons such as ?loving the nation, religion, good relations between nationalities, and opposing the Dalai clique.? In particular, the officials called on fully opposing self-immolations, adding that not opposing self-immolations was equivalent to opposing the Chinese state. Anti self-immolation campaign documents were also distributed at Jhakyung Monastery.

    The ?Cherish life, Abide by Law? document, selective pages of which were received by TCHRD, said ?inciting, misguiding and forcing others to self-immolate will be considered ?intentional homicide?. Those charged of such crimes will be punished under article 232 of Chinese Criminal law.

    Further the document said ?those who create obstacles in the way of PSB officials, medical personnel and others protecting the self-immolators shall be charged with ?intentional homicide,? in accordance with the article 232 of the Criminal Law, and would be given either death sentence, life-imprisonment or ten years of imprisonment. [Those] committing lesser crimes would be sentenced to prison ranging from three to ten years. [See image two]

    Image two

    Image two

    For ?crimes? of inciting the masses to gather and taking out public processions carrying bodies of self-immolators and obstructing the traffic and disrupting public order shall be sentenced under articles 290 and 291 of Criminal Law. [See image three]

    According to Chinese Criminal Law, article 290 is provides that: ?Where people are gathered to disturb public order ? losses are caused, the ringleaders shall be sentenced to fixed-term imprisonment of not less than three years but not more than seven years; the active participants shall be sentenced to fixed-term imprisonment of not more than three years, criminal detention, public surveillance or deprivation of political rights.?

    Article 291 provides that ?where people are gathered to disturb order at railway stations or bus terminals, wharves, civil airports, marketplaces, parks, theaters, cinemas, exhibition halls, sports grounds or other public places, or to block traffic or undermine traffic order, or resist or obstruct public security administrators of the State from carrying out their duties according to law, if the circumstances are serious, the ringleaders shall be sentenced to fixed-term imprisonment of not more than five years, criminal detention or public surveillance.?

    Interestingly, the document says ?those who indulge in beating, smashing, looting and burning at public places will be punished under articles 263 and 275 of Criminal Law on charges of robbing and looting, or intentionally robbing public and private property. Serious cases will be sentenced to minimum of three years and maximum of seven years? prison term, along with monetary fines.? [See image three]

    Image three

    Image three

    The document then goes on to say that ?those who seriously disrupt social stability by making and distributing fake CDS and videos of explosive, venomous, fiery and riotous nature [meaning fake CDs and videos encouraging self-immolations and riots] shall be charged with harming the rules and regulations of society and propagating false rumors and [thus] would be sentenced to five years in prison and subjected to prison-labor. Those who commit serious offences, [however], would be sentenced up to fifteen years in prison.? [See image four]

    Image four

    Image four

    Further, it says ?those who create obstacles in the way of PSB officials and cadres of the various state bureaus performing their lawful duties shall be charged with ?harming the activities of the state/government,? in accordance with the article 277 of the state criminal law, and would be sentenced up to three years in prison, subjected to prison-labor, or monetary fines.? [See image five]

    Image five

    Image five

    In a related development, China announced it has detained 70 Tibetans in Malho Prefecture ?in connection with a string of self-immolations that have occurred since November 2012,? state media reported.?The report said 12 out of 70 Tibetans had been formally arrested and charges would be filed soon against them. Lyu Benchian deputy chief of the Qinghai Provincial Public Security Department?was quoted as saying that ?Tibetan separatists overseas flaunt them [self-immolators] as ?heroes.??

    Interestingly, Chinese state media in a report on the Chinese-appointed Panchen Lama to Inner Mongolia last month said the Panchen Lama ?paid homage to revolutionary martyrs at a monument hall, leaving a note in Tibetan that read, ?Heroes? flesh and blood constitute today?s happy life.?

    The latest arbitrary arrests and detention are part of official attempts to criminalise self-immolation protests by Tibetans and to establish a link between self-immolations in Tibet and the so-called ?Dalai clique? in exile. It is part of a systematic and concerted plan by the Chinese government to avoid addressing the real and urgent issues and grievances raised by self-immolation protesters.

    Source: http://www.tchrd.org/2013/02/anti-self-immolation-propaganda-now-part-of-chinas-patriotic-education-campaign/

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